Helicobacter pylori Infection in Infants and Toddlers in South America: Concordance between [C]Urea Breath Test and Monoclonal H. pylori Stool Antigen Test
نویسندگان
چکیده
Dulciene Maria Magalhães Queiroz, Mayuko Saito, Gifone Aguiar Rocha, Andreia Maria Camargos Rocha, Fabrício Freire Melo, William Checkley, Lúcia Libanez Bessa C. Braga, Igor Simões Silva, Robert H. Gilman, Jean E. Crabtree Laboratory of Research in Bacteriology, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Laboratories of Investigation and Development, Universidad Peruana Cayetano Heredia, Lima, Peru; Biomedical Research Unit, Asociacion Benefica Prisma, Lima, Peru; Clinical Research Unity, Department of Internal Medicine, Universidade Federal do Ceará, Fortaleza, Brazil; Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA; Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom
منابع مشابه
Helicobacter pylori infection in infants and toddlers in South America: concordance between [13C]urea breath test and monoclonal H. pylori stool antigen test.
Accurate noninvasive tests for diagnosing Helicobacter pylori infection in very young children are strongly required. We investigated the agreement between the [(13)C]urea breath test ([(13)C]UBT) and a monoclonal ELISA (HpSA) for detection of H. pylori antigen in stool. From October 2007 to July 2011, we enrolled 414 infants (123 from Brazil and 291 from Peru) of ages 6 to 30 months. Breath an...
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The [(13)C]urea breath test ((13)C-UBT) and Helicobacter pylori stool antigen test (HpSA) for the diagnosis of H. pylori infection in children were validated. The sensitivity, specificity, and positive and negative predictive values were 93.8, 99.1, 97.8, and 98.0%, respectively, for the (13)C-UBT and 96.9, 100, 100, and 98.0%, respectively, for HpSA. Both tests are appropriate for diagnosing H...
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